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Order Code LDHIS Lactate Dehydrogenase (LD) Isoenzymes, Serum

Additional Codes

Mayo Test ID
LD_I

Reporting Name

Lactate Dehydrogenase Isoenzymes, S

Useful For

Investigating a variety of diseases involving the heart, liver, muscle, kidney, lung, and blood

 

Differentiating heart-synthesized lactate dehydrogenase (LD) from liver and other sources

 

Investigating unexplained causes of LD elevations

 

Detection of macro-LD

Specimen Type

Serum


Necessary Information


Patient's age is required.



Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 2 mL divided into 2 tubes each containing 1 mL


Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Ambient (preferred) 7 days
  Refrigerated  48 hours

Reject Due To

Hemolysis

Mild reject; Gross reject

Lipemia

Mild OK; Gross OK

Icterus

NA

Other

NA

Reference Values

LACTATE DEHYDROGENASE (LD)

1-30 days: 135-750 U/L

31 days-11 months: 180-435 U/L

1-3 years: 160-370 U/L

4-6 years: 145-345 U/L

7-9 years: 143-290 U/L

10-12 years: 120-293 U/L

13-15 years: 110-283 U/L

16-17 years: 105-233 U/L

≥18 years: 122-222 U/L

 

LD ISOENZYMES

I (fast band): 17.5-28.3%

II: 30.4-36.4%

III: 19.2-24.8%

IV: 9.6-15.6%

V (slow band): 5.5-12.7%

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Day(s) and Time(s) Performed

LD: Monday through Sunday; Continuously

LD isoenzymes: Tuesday, Thursday, Saturday; 10 a.m.

Method Name

LDI: Electrophoresis Densitometry

LD: Photometric Rate

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83615-LD

83625-LD isoenzymes

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LD_I Lactate Dehydrogenase Isoenzymes, S 42929-0

 

Result ID Test Result Name Result LOINC Value
LD Lactate Dehydrogenase (LD), S 14804-9
305 LD Isoenzymes, S 49279-3
3344 Total LD Activity 14804-9
2282 I, Heart 2536-1
2283 II 2539-5
2285 III 2542-9
2286 IV 2545-2
2287 V, Liver 2548-6

Profile Information

Test ID Reporting Name Available Separately Always Performed
LD Lactate Dehydrogenase (LD), S Yes Yes
LDI LD Isoenzymes, S No Yes

Forms

Biochemical Genetics Patient Information (T602) in Special Instructions.