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HelpOrder Code ASUOE Arsenic Occupational Exposure, with Reflex, Random, Urine
Specimen Required
Patient Preparation:
1. For the 48-hour period prior to start of collection, patient should not eat seafood.
2. High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
3. For industrial exposure monitoring, recommended sampling time is at the end of the work week.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert
Submission Container/Tube: Plastic vial or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 6 mL
Collection Instructions:
1. Collect urine a random urine specimen.
2. See Metals Analysis Specimen Collection and Transport for complete instructions.
Useful For
Preferred screening test for detection of occupational exposure to arsenic in random urine specimens
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ASOU | Arsenic Occupational Exposure | No | Yes |
| CRETR | Creatinine, Random, U | No | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| SPAS | Arsenic Speciation, Random, U | Yes | No |
Testing Algorithm
If total arsenic concentration is 10 mcg/L or greater, then speciation will be performed at an additional charge.
Special Instructions
Method Name
ASOU: Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)
CRETR: Enzymatic Colorimetric Assay
Reporting Name
Arsenic Occ Exp w/Reflex, Random,USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 72 hours |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
ARSENIC
Biological Exposure Indices (BEI): <35 mcg/L at end of work week
CREATININE
≥18 years old: 16-326 mg/dL
Reference values have not been established for patients who are less than 18 years of age.
Method Description
The metal of interest is analyzed by triple-quadrupole inductively coupled plasma mass spectrometry. (Unpublished Mayo method)
Creatinine:
The enzymatic method is based on the determination of sarcosine from creatinine with the aid of creatininase, creatinase, and sarcosine oxidase. The liberated hydrogen peroxide is measured via a modified Trinder reaction using a colorimetric indicator. Optimization of the buffer system and the colorimetric indicator enables the creatinine concentration to be quantified both precisely and specifically.(Package insert: Creatinine plus ver 2. Roche Diagnostics; V15.0, 03/2019)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82175
82570
Day(s) Performed
Monday through Friday