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Order Code IGAS IgA Subclasses, Serum

Reporting Name

IgA Subclasses, S

Useful For

Investigation of immune deficiency due to immunoglobulin A2 deficiency

 

Evaluating patients with anaphylactic transfusion reactions

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation: Fasting: 12 hours, preferred but not required

Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Ambient  7 days
  Frozen  7 days

Reference Values

IgA

1-3.9 years: 5-194 mg/dL

4-6.9 years: 16-210 mg/dL

7-9.9 years: 27-227 mg/dL

10-11.9 years: 35-241 mg/dL

12-13.9 years: 43-252 mg/dL

14-15.9 years: 50-263 mg/dL

16-17.9 years: 57-274 mg/dL

>18 years: 85-499 mg/dL

 

IgA1

1-3.9 years: 6-163 mg/dL

4-6.9 years: 16-186 mg/dL

7-9.9 years: 26-209 mg/dL

10-11.9 years: 34-228 mg/dL

12-13.9 years: 40-243 mg/dL

14-15.9 years: 46-259 mg/dL

16-17.9 years: 53-274 mg/dL

>18 years: 76-328 mg/dL

 

IgA2

1-3.9 years: <0.5-12.4 mg/dL

4-6.9 years: <0.5-25.7 mg/dL

7-9.9 years: 1.5-38.9 mg/dL

10-11.9 years: 2.9-49.9 mg/dL

12-13.9 years: 4.0-58.7 mg/dL

14-15.9 years: 5.2-67.5 mg/dL

16-17.9 years: 6.3-76.3 mg/dL

>18 years: 6.9-114.3 mg/dL

Day(s) Performed

Tuesday, Friday

CPT Code Information

82784

82787 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
IGAS IgA Subclasses, S 87552-6

 

Result ID Test Result Name Result LOINC Value
IGA_ IgA 2458-8
IGA1_ IgA1 6886-6
IGA2_ IgA2 6939-3

Method Description

The determination of soluble antigen concentration by turbidimetric methods involves the reaction with specific antiserum to form insoluble complexes. When light is passed through the suspension formed, a portion of the light is transmitted and focused onto a photodiode by an optical lens system. The amount of transmitted light is indirectly proportional to the specific protein concentration in the test sample. Concentrations are automatically calculated by reference to a calibration curve stored within the instrument.(Package inserts: Optilite IgA Kit. The Binding Site Group, Ltd; 06/2025; Optilite IgA1. The Binding Site Group, Ltd; 03/2024; Optilite IgA2. The Binding Site Group, Ltd; 02/2015)

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

Method Name

Turbidimetry