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Order Code LABGOR, CEASF Carcinoembryonic Antigen (CEA), Spinal Fluid

Additional Codes

Mayo Test Code: CEASF

Reporting Name

Carcinoembryonic Ag (CEA), CSF

Useful For

Detecting meningeal carcinomatosis and intradural or extradural infiltration 

 

Differentiating brain parenchymal metastasis from adenocarcinoma or squamous-cell carcinoma

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

CSF


Specimen Required


Collection Container/Tube: Sterile vial

Submission Container/Tube: 13 x 75-mm tube

Specimen Volume: 0.5 mL


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Reference Values

<0.6 ng/mL

Tumor markers are not specific for malignancy, and values may vary by method.

Day(s) Performed

Monday through Saturday

CPT Code Information

82378

Method Description

The Access carcinoembryonic antigen (CEA) assay is a 2-site immunoenzymatic sandwich assay using 2 mouse monoclonal anti-CEA antibodies (MAb) that react with different epitopes of CEA. A sample is added to a reaction vessel, along with the first anti-CEA MAb-alkaline phosphatase conjugate and the second anti-CEA MAb bound to paramagnetic particles. The incubation is followed by a magnetic separation and washing. The chemiluminescent substrate Lumi-Phos 530 is added to the vessel and light generated by the reaction is measured with a luminometer. The light production is proportional to the concentration of CEA in the sample. The amount of analyte in the sample is determined by means of a stored, multipoint calibrator curve.(Package insert: Access CEA, Beckman Coulter Inc; 2020)

Reject Due To

No specimen should be rejected

Method Name

Immunoenzymatic Assay

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.