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HelpOrder Code LABGOR, PBLI Plasma Cell Assessment, Blood
Reporting Name
Plasma Cell Assessment, BUseful For
Detecting peripheral blood involvement by plasma cell proliferative disorders
Establishing the diagnosis of and determining prognosis for plasma cell proliferative disorders
Testing Algorithm
The following algorithms are available:
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Whole bloodShipping Instructions
Specimen must arrive within 3 days of collection.
Necessary Information
Date and time of collection are required.
Specimen Required
Container/Tube:
Preferred: Green top (sodium heparin)
Acceptable: Lavender top (EDTA)
Specimen Volume: 10 mL
Collection Instructions:
1. Do not centrifuge.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Minimum Volume
4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Ambient (preferred) | 72 hours |
| Refrigerated | 72 hours |
Special Instructions
Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Saturday
CPT Code Information
88184-Flow cytometry, cell surface, cytoplasmic
88185 x 5-Each additional marker
88187-Flow cytometry, interpretation; 2 to 8 markers
Method Description
The plasma cell immunoglobulin light chain restriction assessment is performed by 6-color flow cytometry using a single assay tube containing antibodies to kappa Ig light chain, lambda Ig light chain, CD19, CD38, CD45, and CD138. CD38 and CD138 are used to gate on the plasma cells and anti-kappa and anti-lambda are used to identify cytoplasmic Ig light chains. The flow cytometric screen will report the presence or absence of a detectable plasma cell population with immunoglobulin light chain restriction (clonality).(Unpublished Mayo method)
Reject Due To
| Gross hemolysis | Reject |
Method Name
Flow Cytometry
Forms
If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.