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Order Code LABUCTDS Drug Detection Panel, Umbilical Cord Tissue, Qualitative

Additional Codes

Detect and document maternal drug use. Useful during approximately the last trimester of a full-term pregnancy. To test for marijuana metabolite, see Marijuana Metabolite, Umbilical Cord Tissue, Qualitative (LABUCTTHC). To test for ethyl glucuronide, see Ethyl Glucuronide, Umbilical Cord Tissue, Qualitative (LABUCTETG).

Specimen Requirements

Collect:

Umbilical Cord (At least 8 inches, approximately the width of a sheet of paper.)
 

Specimen Preparation:

Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or water. Pat the cord dry and transport at least 8 inches of umbilical cord in a routine urine collection cup.

Storage/Transport Temperature:
Refrigerated.

Unacceptable Conditions:
Cords soaking in blood or other fluid. Formalin fixed. Tissue that is obviously decomposed.

 

Stability:

Ambient: 1 week; Refrigerated: 3 weeks; Frozen: 1 year

 

Reference Values

Effective February 20, 2018

Drugs covered and range of cutoff concentrations.
Drugs/Drug Classes Cutoff Concentrations (ng/g) Drugs/Drug Classes Cutoff Concentrations (ng/g)
Buprenorphine 1 Amphetamine 5
Norbuprenorphine 0.5 Benzoylecgonine 0.5
    m-OH-Benzoylecgonine 1
Codeine 0.5 Cocaethylene 1
Dihydrocodeine 1 Cocaine 0.5
Fentanyl 0.5 MDMA (Ecstasy) 5
Hydrocodone 0.5 Methamphetamine 5
Norhydrocodone 1 Phentermine 8
Hydromorphone 0.5 Alprazolam 0.5
Meperidine 2 Alpha-OH-Alprazolam 0.5
Methadone 2 Butalbital 25
Methadone metabolite 1 Clonazepam 1
6-Acetylmorphine 1 7-Aminoclonazepam 1
Morphine 0.5 Diazepam 1
Naloxone 1 Lorazepam 5
Oxycodone 0.5 Midazolam 1
Noroxycodone 1 Alpha-OH-Midazolam 2
Oxymorphone 0.5 Nordiazepam 1
Noroxymorphone 0.5 Oxazepam 2
Propoxyphene 1 Phenobarbital 75
Tapentadol 2 Temazepam 1
Tramadol 2 Zolpidem 0.5
N-desmethyltramadol 2 Phencyclidine (PCP) 1
O-desmethyltramadol 2 Gabapentin 10

Day(s) Test Set Up

Sunday to Saturaday
Reports with 1-3 days upon arrival at ARUP laboratory

Performing Laboratory

ARUP Reference Laboratory

Methodology

Qualitative Liquid Chromatography/Tandem Mass Spectrometry

Test Classification and CPT Coding

80326; 80347; 80364; 80355

Interpretive Data

Detection of drugs in umbilical cord tissue is intended to reflect maternal drug use during approximately the last trimester of a full-term pregnancy. The pattern and frequency of drug(s) used by the mother cannot be determined by this test. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drugs in umbilical cord tissue depends on extent of maternal drug use, as well as drug stability, unique characteristics of drug deposition in umbilical cord tissue, and the performance of the analytical method. Drugs administered during labor and delivery may be detected. Detection of drugs in umbilical cord tissue does not insinuate impairment and may not affect outcomes for the infant. Interpretive questions should be directed to the laboratory.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
 

Compliance Category

Laboratory Developed Test (LDT)