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HelpOrder Code LACS1 Lactate, Plasma
Ordering Guidance
This test does not measure D-lactate, an uncommon, often undiagnosed cause of lactic acidosis. If D-lactate testing is needed, order DLAC / D-Lactate, Plasma.
Necessary Information
Patient's age and sex are required.
Specimen Required
Collection Container/Tube: Gray top (potassium oxalate/sodium fluoride)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collection must be at least 1 mL in a 2-mL collection tube or at least 2 mL in a 4-mL collection tube.
2. Centrifuge and aliquot plasma into plastic vial.
Useful For
Diagnosing and monitoring patients with lactic acidosis
Method Name
Colorimetric
Reporting Name
Lactate, PSpecimen Type
Plasma NaFl-KOxSpecimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma NaFl-KOx | Refrigerated (preferred) | 14 days | |
| Ambient | 8 hours |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
0-90 days (<3 months): 0.0-3.3 mmol/L
3-24 months: 0.0-3.1 mmol/L
>24 months-18 years: 0.0-2.2 mmol/L
>18 years: 0.5-2.2 mmol/L
Method Description
Lactate concentration is determined using an enzymatic colorimetric method. L-lactate is oxidized to pyruvate by the specific enzyme lactate oxidase. Peroxidase is used to generate a colored dye using the hydrogen peroxide generated in the first reaction. The intensity of the color formed is directly proportional to the L-lactate concentration. It is determined by measuring the increase in absorbance.(Package insert: Roche Diagnostics, Indianapolis IN, 02/2016)
Day(s) Performed
Monday through Sunday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83605