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HelpOrder Code MURA Lysozyme (Muramidase), Plasma
Specimen Required
Collection Container/Tube: Lavender top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions:
1. Centrifuge and aliquot plasma into a plastic vial within 2 hours of collection.
2. Freeze immediately after transferring.
Useful For
As a screening test for ocular sarcoidosis
Confirming marked increases in the granulocyte or monocyte pools as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis
Following the course of therapy in cases of chronic granulocytic or chronic monocytic leukemias
Method Name
Turbidimetric
Reporting Name
Lysozyme (Muramidase), PSpecimen Type
Plasma EDTASpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma EDTA | Frozen | 21 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
≥12 months: 2.6-6.0 mcg/mL
Reference values have not been established for patients who are less than12 months of age.
Method Description
The term lysozyme is derived from the ability of this enzyme to dissolve the walls of certain bacteria, including Micrococcus lysodeikticus. This organism is suspended in buffer, and the sample is added. The resulting decrease in turbidity is measured spectrophotometrically. The rate of clearing is a reflection of the concentration of the enzyme.(Litwack G: Photometric determination of lysozyme activity. Proc Soc Exp Biol Med. 1955;89(3):401-403)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85549
Day(s) Performed
Monday through Friday
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Benign Hematology Test Request (T755)