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Order Code 10_IS Factor X Inhibitor Screen, Plasma

Method Name

Only orderable as a reflex. For more information see:

10INE / Factor X Inhibitor Evaluation, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

APROL / Prolonged Clot Time Profile, Plasma

 

Optical Clot-Based

Reporting Name

Factor X Inhib Scrn

Specimen Type

Plasma Na Cit

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Only orderable as a reflex. For more information see:

10INE / Factor X Inhibitor Evaluation, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

APROL / Prolonged Clot Time Profile, Plasma

 

Negative

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

85335


Ordering Guidance


 



Specimen Required


Only orderable as a reflex. For more information see:

10INE / Factor X Inhibitor Evaluation, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

APROL / Prolonged Clot Time Profile, Plasma

 

For more information see Coagulation Guidelines for Specimen Handling and Processing.


Useful For

Detecting the presence of a specific factor inhibitor directed against coagulation factor X

Method Description

The factor X inhibitor screen is performed on the Instrumentation Laboratory ACL TOP. The assay consists of measuring the factor X activity (prothrombin time based assay) before and after incubation of a mixture of normal plasma and patient's plasma for 1 hour at 37° C. Interpretation of the presence or absence of the indication of a factor X inhibitor is determined by comparing the factor X activity results and the calculated expected values.(Owen CA Jr, Bowie EJW, Thompson JH Jr. The Diagnosis of Bleeding Disorders. 2nd ed. Little, Brown, and Company; 1975:14-144; Meijer P, Verbruggen HW, Spannagi M. Clotting factors and inhibitors: Assays and Interpretation. Chapter 33. In: Kottke-Marchant K, ed.  Laboratory Hematology Practice. Wiley Blackwell Publishing;  2012:435-446)