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Order Code ABADL Adalimumab Antibody, Serum


Specimen Required


Only orderable as part of a profile. For more information see ADALP / Adalimumab Quantitative Antibody, Serum.

 

Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL Serum

Collection Instructions:

1. Draw blood immediately before the next dose of drug administration (trough specimen).

2. Centrifuge and aliquot serum into a plastic vial.


Useful For

Therapeutic drug monitoring of adalimumab

 

Quantifying adalimumab antibodies as part of a profile evaluating patients for loss of response, partial response on initiation of therapy, autoimmune or hypersensitivity reactions, primary nonresponse, reintroduction after drug holiday, endoscopic/computed tomography enterography recurrence (in inflammatory bowel disease), acute infusion reactions and proactive monitoring

 

This test does not differentiate between the originator and biosimilar products.

Testing Algorithm

When this test is ordered, adalimumab quantitation and testing for antibodies-to-adalimumab will always be performed.

Method Name

Only orderable as part of a profile. For more information see ADALP / Adalimumab Quantitative Antibody, Serum.

 

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Adalimumab Ab, S

Specimen Type

Serum

Specimen Minimum Volume

Serum: 0.35 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Heat-treated Reject
Gross icterus OK

Method Description

Testing for antibodies-to-adalimumab is performed using a laboratory-developed immunoassay.(Unpublished Mayo method)

Day(s) Performed

Tuesday, Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83520

LOINC Code Information

Result ID Test Result Name Result LOINC Value
ABADL Adalimumab Ab, S 90779-0