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HelpOrder Code ALKLC Anaplastic Lymphoma Kinase for Lung Cancer, Immunohistochemistry
Shipping Instructions
Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.
Necessary Information
A pathology/diagnostic report and a brief history, including primary site of neoplasm, are required.
Specimen Required
Specimen Type: Tissue
Supplies: Pathology Packaging Kit (T554)
Submit:
Formalin-fixed, paraffin-embedded tissue block
OR
3 Unstained glass, "positively charged" slides with 4-microns formalin-fixed, paraffin-embedded tissue
Additional Information: One slide will be stained with hematoxylin and eosin and returned.
Useful For
Identification of anaplastic lymphoma kinase (ALK) expression
Prediction of tumor response to targeted therapy of non-small cell lung carcinomas.
Method Name
Immunohistochemistry (IHC)
Reporting Name
ALK for Lung Cancer IHCSpecimen Type
SpecialSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Special | Ambient (preferred) | |
| Refrigerated | ||
Reject Due To
| Wet/frozen tissue | Reject |
| Decalcified paraffin embedded tissue | Reject |
| Cytology smears | Reject |
| Nonformalin fixed tissue including alcohol-formalin-acetic acid (AFA), 95% ethanol, PREFER fixatives or zinc formalin | Reject |
| Nonparaffin embedded tissue | Reject |
| Noncharged slides | Reject |
| ProbeOn slides | Reject |
| Snowcoat slides | Reject |
Method Description
Immunohistochemistry on sections of paraffin-embedded tissue.(Unpublished Mayo method)
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
88342-Primary
88341-If additional IHC
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ALKLC | ALK for Lung Cancer IHC | 47303-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 615714 | Interpretation | 59465-5 |
| 615715 | Participated in the Interpretation | No LOINC Needed |
| 615716 | Report electronically signed by | 19139-5 |
| 615717 | Material Received | 81178-6 |
| 615718 | Disclaimer | 62364-5 |
| 615719 | Case Number | 80398-1 |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| IHPCA | IHC Additional | No | No |
| IHPCI | IHC Initial | No | No |
Testing Algorithm
For the initial immunohistochemistry (IHC) stain performed, the appropriate bill-only test ID will be added and charged (IHPCI). For each additional IHC stain performed, an additional bill-only test ID will be added and charged (IHPCA).
Forms
If not ordering electronically, complete, print, and send a Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763) with the specimen.