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HelpOrder Code AMH1 Antimullerian Hormone, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Useful For
Assessing ovarian status, including ovarian reserve and responsiveness, as part of an evaluation for infertility and assisted reproduction protocols
Assessment of menopausal status, including premature ovarian failure
Evaluation of infants with ambiguous genitalia and other intersex conditions
Evaluating testicular function in infants and children
Monitoring individuals with antimullerian hormone-secreting ovarian granulosa cell tumors
Method Name
Electrochemiluminescent Immunoassay (ECLIA)
Reporting Name
Antimullerian Hormone, SSpecimen Type
SerumSpecimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 180 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | Reject-acceptable to 1000 mg/dL |
| Gross lipemia | OK |
| Gross icterus | Reject-acceptable to 66 mg/dL |
Reference Values
Males
<2 years: 18-283 ng/mL
2-12 years: 8.9-109 ng/mL
>12 years: <13 ng/mL
Females
<3 years: 0.11-4.2 ng/mL
3-6 years: 0.21-4.9 ng/mL
7-11 years: 0.36-5.9 ng/mL
12-14 years: 0.49-6.9 ng/mL
15-19 years: 0.62-7.8 ng/mL
20-24 years: 1.2-12 ng/mL
25-29 years: 0.89-9.9 ng/mL
30-34 years: 0.58-8.1 ng/mL
35-39 years: 0.15-7.5 ng/mL
40-44 years: 0.03-5.5 ng/mL
45-50 years: <2.6 ng/mL
51-55 years: <0.88 ng/mL
>55 years: <0.03 ng/mL
Method Description
The Roche Elecsys AMH (anti-Mullerian hormone) assay is a 2-site immunometric sandwich assay using electrochemiluminescence detection. Patient specimen, biotinylated monoclonal AMH-specific antibody, and monoclonal AMH-specific antibody labeled with a ruthenium react to form a complex. Streptavidin-coated microparticles act as the solid phase to which the complex becomes bound. Voltage is applied to the electrode inducing a chemiluminescent emission from the ruthenium, which is then measured against a calibration curve to determine the amount of AMH in the patient specimen.(Package insert: Elecsys AMH, Roche Diagnostics; 2.0 English, 10/2022)
Day(s) Performed
Monday through Saturday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82166
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.