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HelpOrder Code HALO Haloperidol, Serum
Reporting Name
Haloperidol, SUseful For
Optimizing haloperidol dosage
Monitoring patient compliance
Assessing toxicity
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Draw blood immediately before next scheduled dose.
2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Reference Values
Haloperidol:
5-17 ng/mL
Reduced Haloperidol:
10-80 ng/mL
Day(s) Performed
Tuesday
CPT Code Information
80173
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HALO | Haloperidol, S | 87550-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80339 | Haloperidol, S | 3669-9 |
| 169 | Reduced Haloperidol | 38364-6 |
Method Description
Haloperidol and reduced haloperidol, its major metabolite, are extracted from serum utilizing protein precipitation and diluted by the addition of internal standard (haloperidol-d4 and reduced haloperidol-d4). Analysis of the supernatant is performed on a liquid chromatography tandem mass spectrometry system.(Unpublished Mayo method)
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.