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Order Code HALO Haloperidol, Serum

Reporting Name

Haloperidol, S

Useful For

Optimizing haloperidol dosage

 

Monitoring patient compliance

 

Assessing toxicity

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Haloperidol:

5-17 ng/mL

 

Reduced Haloperidol:

10-80 ng/mL

Day(s) Performed

Tuesday

CPT Code Information

80173

Method Description

Haloperidol and reduced haloperidol, its major metabolite, are extracted from serum utilizing protein precipitation and diluted by the addition of internal standard (haloperidol-d4 and reduced haloperidol-d4). Analysis of the supernate is performed on a liquid chromatography tandem mass spectrometry system.(Unpublished Mayo method)

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.