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HelpOrder Code HCQ Hydroxychloroquine, Serum
Useful For
Monitoring serum hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Hydroxychloroquine, SSpecimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (gel tubes/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Collect specimen immediately before next scheduled dose.
2. Within 2 hours of collection, centrifuge, and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 21 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
For suppressive treatment of malaria, suggested plasma or serum concentrations should be >10 ng/mL.
For systemic lupus erythematosus, proposed serum target concentrations should be ≥500 ng/mL.
Method Description
Samples are extracted with analyte detection by tandem mass spectrometry.(Unpublished Mayo method)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80220
Day(s) Performed
Monday, Wednesday, Friday
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.