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HelpOrder Code HCQWB Hydroxychloroquine, Blood
Specimen Required
Container/Tube: Lavender top (EDTA)
Specimen Volume: 1 mL
Collection Instructions:
1. Collect specimen immediately before next scheduled dose.
2. Send whole blood specimen in original tube. Do not aliquot.
Useful For
Monitoring whole blood hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Hydroxychloroquine, BSpecimen Type
Whole Blood EDTASpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood EDTA | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
| Clotted specimens | Reject |
Reference Values
≥200 ng/mL
Method Description
Reagent is added to the whole blood sample following the addition of deuterium-labeled internal standard. The mixture is centrifuged, and a portion of the supernatant is diluted with mobile phase for analysis and detection by liquid chromatography tandem mass spectroscopy.(Unpublished Mayo method)
Day(s) Performed
Tuesday, Thursday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80220
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HCQWB | Hydroxychloroquine, B | 95921-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623295 | Hydroxychloroquine, B | 95921-3 |