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Order Code HEXP Iohexol, Plasma

Reporting Name

Iohexol, P

Useful For

Determining glomerular filtration rate in plasma specimens

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Plasma Heparin


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Green top (heparin)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot plasma into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Heparin Refrigerated (preferred) 7 days
  Frozen  35 days
  Ambient  7 days

Reference Values

Not applicable

Day(s) Performed

Monday through Friday

CPT Code Information

82542

Method Description

Blood specimens are obtained after subcutaneous injection of non-radiolabeled iohexol. Iohexol results are acquired via a liquid chromatography tandem mass spectrometry (LC-MS/MS) system. A ThermoFisher LX-2 Cohesive high-performance liquid chromatography system and an ABSciex 5500 MS/MS are used for analysis.(Seegmiller JC, Burns BE, Lieske JC, et al. Discordant glomerular filtration rate determinations between iothalamate and iohexol renal clearances. Poster presented at: Renal Week 2010. 43rd Annual Meeting of the American Society of Nephrology; November 16-21, 2010; Denver, CO)

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.