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Order Code HGUCR Mercury/Creatinine Ratio, Random, Urine


Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Metals Analysis Specimen Collection and Transport for complete instructions.


Useful For

Detecting mercury toxicity, a toxic heavy metal, using random urine specimens

Profile Information

Test ID Reporting Name Available Separately Always Performed
HGCU Mercury/Creatinine Ratio, U No Yes
CRETR Creatinine, Random, U No Yes

Method Name

HGCU: Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Mercury/Creat Ratio, Random,U

Specimen Type

Urine

Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

MERCURY/CREATININE:

0-17 years: Not established

≥18 years: <2 mcg/g creatinine

 

CREATININE:

≥18 years: 16-326 mg/dL

Reference values have not been established for patients who are younger than 18 years of age. 

Method Description

Mercury:

The metal of interest is analyzed by triple-quadrupole inductively coupled plasma mass spectrometry.(Unpublished Mayo method)

 

Creatinine:

The enzymatic method is based on the determination of sarcosine from creatinine with the aid of creatininase, creatinase, and sarcosine oxidase. The liberated hydrogen peroxide is measured via a modified Trinder reaction using a colorimetric indicator. Optimization of the buffer system and the colorimetric indicator enables the creatinine concentration to be quantified both precisely and specifically.(Package insert: Creatinine plus ver 2. Roche Diagnostics; V15.0, 03/2019)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83825

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HGUCR Mercury/Creat Ratio, Random,U 13465-0

 

Result ID Test Result Name Result LOINC Value
608903 Mercury/Creatinine Ratio, U 13465-0
CRETR Creatinine, Random, U 2161-8

Day(s) Performed

Monday through Friday