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Order Code LAB11 Creatinine, Plasma or Serum

Additional Codes

Test Name in EPIC

EPIC Test Code           

Mnemonic

RV CREATININE

LAB11

CREA

 

Useful For

Serum creatinine measurement is used in estimating GFR for people with chronic kidney disease (CKD) and those with risk factors for CKD (diabetes, hypertension, cardiovascular disease, and family history of kidney disease)

  • Diagnosing and monitoring treatment of acute and chronic renal diseases
  • Adjusting dosage of renally excreted medications
  • Monitoring renal transplant recipients

Specimen Requirements

Special Note:  Plasma or serum must be removed from cells within 4 hours of collection

 

Specimen Type: Plasma or Serum

Collection Container/Tube:

Preferred:  Green-top (lithium heparin) gel tube 

Acceptable:  Plain, red-top tube or SST

Specimen Volume: 2 mL

Pediatric (minimum) volume: 0.5 mL

Specimen Stability

Specimen Type Temperature Stability                  
Plasma or Serum Ambient 5 days
  Refrigerated (preferred) 30 days
  Frozen 6 months

Reference Values

  • Male:  0.66 - 1.25 mg/dL
  • Female:  0.52 - 1.04 mg/dL
  • Unspecified: 0.52-1.25 mg/dL
  • Critical value (automatic call-back):  > 5.00 mg/dL

 

GFR CALCULATED (mL/min/1.73 m2)

  • Stage 1:  ≥ 90 mL/min
  • Stage 2:  60 - 89 mL/min
  • Stage 3:  30 - 59 mL/min
  • Stage 4:  15 - 29 mL/min
  • Stage 5:  ≤14 mL/min

When creatinine is ordered, a GFR will automatically be calculated on all patients >18 years old.

The MDRD GFR formula is only valid for adults between ages 18 and 85.

Interferences

  • Use of this testing is not recommended for patients undergoing treatment with phenindione, due to the potential for falsely depressed results.
  • N-acetyl-p-benzoquinone, a metabolite of acetaminophen, in concentrations of >10 mg/L, correlating to toxic levels of acetaminophen, may lead to falsely depressed results.

Methodology

Two-point rate

  • Glomerular Filtration Rate (GFR), Estimated: Calculated on patients between 18 and 85 years old.
  • CKD-EPI 2021 equation:  GFR = 142 x min (Scr/K, 1)a  x max (Scr/K, 1)-1.200 x 0.9938age x 1.012 (if non-male) 

Day(s) Test Set Up

Monday through Sunday

Performing Laboratory

Ridgeview Medical Center Laboratory

Two Twelve Medical Center Laboratory

Ridgeview Sibley Medical Center Laboratory

Ridgeview Le Sueur Medical Center Laboratory

Test Classification and CPT Coding

82565 - Creatinine

No CPT code - GFR (calculation)