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HelpOrder Code LAB1324 Immunoglobulin E (IgE), Serum
Additional Codes
| Mayo Test ID |
|---|
| IGE |
Reporting Name
Immunoglobulin E (IgE), SUseful For
Evaluating patients with suspected diseases associated with elevations in total IgE, including allergic disease, primary immunodeficiencies, infections, malignancies, or other inflammatory diseases
Diagnostic evaluation of patients with suspected allergic bronchopulmonary aspergillosis
Identifying candidates for omalizumab (anti-IgE) therapy
Specimen Type
SerumOrdering Guidance
For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
For only total IgE: 0.3 mL
For total IgE and more than 1 allergen: 0.05 mL x number of allergen-specific tests + 0.25 mL dead space
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 90 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
Reference Values
0-5 months: ≤13 kU/L
6-11 months: ≤34 kU/L
1 and 2 years: ≤97 kU/L
3 years: ≤199 kU/L
4-6 years: ≤307 kU/L
7 and 8 years: ≤403 kU/L
9-12 years: ≤696 kU/L
13-15 years: ≤629 kU/L
16 and 17 years : ≤537 kU/L
18 years or older: ≤214 kU/L
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Day(s) Performed
Monday through Friday
Method Name
Fluorescence Enzyme Immunoassay (FEIA)
CPT Code Information
82785
Method Description
Anti-IgE, covalently coupled to ImmunoCAP, reacts with the IgE in a serum specimen. After washing, enzyme-labeled anti-IgE antibodies are added to form a complex. After incubation, unbound enzyme-labeled anti-IgE is washed away and the bound complex is incubated with a developing agent. After stopping the reaction, fluorescence of the eluate in the well is measured. The fluorescence is directly proportional to the concentration of IgE in the test specimen.(Package insert: Phadia CAP System IgE FEIA. Phadia; revised 04/2019)