Home
HelpOrder Code LAB1524 Vitamin E, Serum
Useful For
Monitoring of Vitamin E supplementation/treatment
Potentially detecting Vitamin E overdoses
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Vitamin E, SSpecimen Type
SerumShipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Patient Preparation:
Fasting: 12 hours, required; infants should have specimen collected before next feeding
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Amber vial
Specimen Volume: 0.5 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into light protected plastic vial.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 44 days | LIGHT PROTECTED |
| Frozen | 44 days | LIGHT PROTECTED | |
| Ambient | 7 days | LIGHT PROTECTED |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Reference Values
0-17 years: 3.8-18.4 mg/L
≥18 years: 5.5-17.0 mg/L
Method Description
Deuterated vitamin E (d6-alpha-tocopherol) is added to serum as an internal standard. Vitamin E (alpha-tocopherol) and the deuterated internal standard are extracted from the specimens and analyzed by liquid chromatography-tandem mass spectrometry.(Unpublished Mayo method)
Day(s) Performed
Sunday through Friday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84446
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.