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HelpOrder Code LAB3815 Methadone Confirmation, Random, Urine
Additional Codes
Mayo Code: MTDNU
Reporting Name
Methadone Confirmation, UUseful For
Monitoring for compliance of methadone treatment for analgesia or drug rehabilitation
Assessing compliance with rehabilitation programs by urine measurement of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
Specimen Type
UrineOrdering Guidance
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order MTDNX / Methadone Confirmation, Chain of Custody, Random, Urine.
2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.
3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume
2.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Reference Values
Negative
Cutoff concentrations:
METHADONE BY GC-MS
<100 ng/mL
2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE GC-MS
<100 ng/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Day(s) Performed
Tuesday, Thursday
Method Name
Gas Chromatography Mass Spectrometry (GC-MS) Confirmation with Quantitation
CPT Code Information
80358
G0480 (if appropriate)
Method Description
Confirmation testing is performed by gas chromatography mass spectrometry, solid phase extraction.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.