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HelpOrder Code LAB3851 Cocaine and Metabolite Confirmation, Random, Urine
Additional Codes
Mayo Code: COKEU
Reporting Name
Cocaine and metabolite Conf, UUseful For
Detecting and confirming drug abuse involving cocaine
This test is not intended for employment-related testing.
Specimen Type
UrineOrdering Guidance
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order COKEX / Cocaine and Metabolite Confirmation, Chain of Custody, Random, Urine.
2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.
3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Plastic urine container
Submission Container/Tube: 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information:
1. No specimen substitutions.
2. STAT requests are not accepted for this test.
Specimen Minimum Volume
5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 14 days |
| Frozen | 14 days | |
| Ambient | 72 hours |
Reject Due To
| All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
Negative (Positive results are reported with a quantitative result.)
Cutoff concentrations by gas chromatography mass spectrometry:
Cocaine: 50 ng/mL
Benzoylecgonine: 50 ng/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Day(s) Performed
Monday, Wednesday, Thursday, Friday
Method Name
Gas Chromatography Mass Spectrometry (GC-MS) Confirmation with Quantitation
CPT Code Information
G0480
80353 (if appropriate for select payers)
Method Description
To accommodate the need to confirm specifically the presence of cocaine in urine, Mayo Clinic Laboratories offers a single test to identify cocaine and its principal metabolite, benzoylecgonine, by using gas chromatography mass spectrometry.(Chinn DM, Crouch DJ, Peat MA, et al. Gas chromatography-chemical ionization mass spectrometry of cocaine and its metabolites in biological fluids. J Anal Toxicol 1980;4:37-42; Rosado T, Goncalves A, Margalho C, Barroso M, Gallardo E. Rapid analysis of cocaine and metabolites in urine using microextraction in packed sorbent and GC/MS. Anal Bioanal Chem. 2017;409(8):2051-2063. doi:10.1007/s00216-016-0152-2)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.