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HelpOrder Code LAB5797 Fluoxetine, Serum
Additional Codes
| Mayo Test ID |
|---|
| FLUOX |
Reporting Name
Fluoxetine, SUseful For
Monitoring serum concentration of fluoxetine during therapy
Evaluating potential toxicity
Evaluating patient compliance
Specimen Type
Serum RedSpecimen Required
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Draw blood immediately before the next scheduled dose (trough).
2. Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Fluoxetine + Norfluoxetine: 120-500 ng/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Day(s) Performed
Wednesday
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
CPT Code Information
80299
Method Description
Serum samples containing fluoxetine and norfluoxetine are diluted in an aqueous solution containing deuterated internal standards and then injected onto a high-turbulence liquid chromatography system for online extraction. Detection is by tandem mass spectrometry.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.