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Order Code LAB5948 Delta-8 and Delta-9-Carboxy-Tetrahydrocannabinol (THC) Confirmation, Random, Urine

Additional Codes

Mayo Code: THCU

Reporting Name

Carboxy-THC Confirmation, U

Useful For

Detection and confirmation of drug use of cannabis/marijuana and to specifically identify and quantify delta-8-carboxy tetrahydrocannabinol (THC-COOH) and delta-9-THC-COOH

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order THCX / Delta-8 and Delta-9-Carboxy-Tetrahydrocannabinol (THC) Confirmation, Chain of Custody, Random, Urine

 

Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, order, ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To

Gross hemolysis OK
Gross icterus Reject

Reference Values

Not Detected

 

Cutoff concentration:

DELTA-8 CARBOXY-TETRAHYDROCANNABINOL (THC) by LC-MS/MS: <5.0 ng/mL

DELTA-9 CARBOXY-TETRAHYDROCANNABINOL (THC) by LC-MS/MS: <5.0 ng/mL

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Day(s) Performed

Monday through Friday

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

CPT Code Information

80349

G0480 (if appropriate)

Method Description

Carboxy tetrahydrocannabinol (THC-COOH) is extracted from urine by making the urine alkaline to hydrolyze THC-COOH glucuronide. The hydrolyzed samples are diluted for analysis by liquid chromatography tandem mass spectrometry using selected ion monitoring.(Unpublished Mayo method)

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Therapeutics Test Request (T831)