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HelpOrder Code LAB6220 Amiodarone, Serum
Additional Codes
| Mayo Test ID |
|---|
| AMIO |
Reporting Name
Amiodarone, SUseful For
Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact
Evaluating possible amiodarone toxicity
Assessing patient compliance
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Draw blood no sooner than 12 hours (trough value) after last dose or immediately before next scheduled dose.
2. Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 24 hours |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
AMIODARONE
Trough Value
0.5-2.0 mcg/mL: Therapeutic concentration
>2.5 mcg/mL: Toxic concentration
DESETHYLAMIODARONE
No therapeutic range established for desethylamiodarone; activity and serum concentration are similar to parent drug.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Day(s) Performed
Monday through Friday
Method Name
Liquid Chromatography Mass Spectrometry (LC-MS/MS)
CPT Code Information
80151
Method Description
Protein is precipitated from serum and following centrifugation the supernatant is diluted and analyzed by liquid chromatography tandem mass spectrometry.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send a one of the following with the specimen:
-Therapeutics Test Request (T831)
-Cardiovascular Test Request (T724)