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HelpOrder Code LABCCPTM Prothrombin Time Mix 1:1, Plasma
Additional Codes
Mayo Test Code: PTMSC
Necessary Information
Heparin or warfarin therapy should be noted.
Specimen Required
Only orderable as a reflex. For more information see:
ALUPP / Lupus Anticoagulant Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
AATHR / Thrombophilia Profile, Plasma and Whole Blood
APROL / Prolonged Clot Time Profile, Plasma
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
Useful For
Screening test to detect a deficiency of one or more of the clotting factors of the extrinsic coagulation system (I, II, V, VII, X) due to hereditary deficiency or acquired conditions such as liver disease, vitamin K deficiency, or a specific factor inhibitor
Determining the cause of a prolonged prothrombin time, factor deficiency versus factor inhibitor
Method Name
Only orderable as a reflex. For more information see:
ALUPP / Lupus Anticoagulant Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
AATHR / Thrombophilia Profile, Plasma and Whole Blood
APROL / Prolonged Clot Time Profile, Plasma
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
Optical Clot-Based
Reporting Name
PT Mix 1:1Specimen Type
Plasma Na CitSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
Only orderable as a reflex. For more information see:
ALUPP / Lupus Anticoagulant Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
AATHR / Thrombophilia Profile, Plasma and Whole Blood
APROL / Prolonged Clot Time Profile, Plasma
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
9.4-12.5 seconds
Method Description
The prothrombin time (PT) mix assay is performed on the Instrumentation Laboratory ACL TOP. Patient plasma is combined in a 1:1 ratio with normal pooled plasma then incubated. After a specified incubation time, a PT reagent containing phospholipid, calcium chloride, buffer, and a preservative is added to trigger the coagulation process in the mixture. Subsequently, the time to clot formation is measured optically using a wavelength of 671 nm.(Package insert: HemosIL RecombiPlasTin 2G. Instrumentation Laboratory Company; 03/2019)
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85611
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PTMSC | PT Mix 1:1 | 5959-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| PTMSC | PT Mix 1:1 | 5959-2 |