Home
HelpOrder Code LABFHLCG Immunoglobulin G (IgG) Heavy and Light Chain (HLC) Pairs, Kappa and Lambda with Ratio
Additional Codes
FHLCG, LABFHLCG
Specimen Required
Specimen Type: Serum
Container/Tube: Â Red top or SST
Specimen Volume: 0.75 mL
Collection Instructions: Draw blood in a plain red-top tube, serum gel tube(s) is also acceptable. Separate serum immediately after coagulation (30 minutes) to prevent hemolysis. Send 0.75 mL of serum refrigerated in a plastic vial.
NOTE: Patient should be fasting for eight hours to avoid lipemic sample interference.
Useful For
Heavy and light chain pair quantitation may be useful for:
1. Distinguishing between broadly migrating monoclonal proteins and restricted polyclonal immunoglobulin patterns on serum electrophoresis.
2. Quantitating monoclonal IgG proteins that are difficult to quantitate using serum protein electrophoresis alone.
3. Providing a more specific quantitation of the monoclonal protein than total IgG measurements alone.
Method Name
Turbidimetric
Reporting Name
IgG Heavy Light Chains (HLC), SSpecimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Ambient | 14 days | ||
| Frozen | 14 days |
Reject Due To
| Hemolysis | Mild reject; Gross reject |
| Lipemia | Mild reject; Gross reject |
| Icterus | NA |
| Other | Microbially-contaminated specimen; specimen containing particulate matter |
Reference Values
IgG Kappa (g/L): 4.03 - 9.78
IgG Lambda (g/L): 1.97 - 5.71
IgG Kappa:IgG Lambda ratio: 0.98 - 2.75
Day(s) Performed
Tuesday, Friday
Performing Laboratory
LabCorp BurlingtonCPT Code Information
83883 x 2
Specimen Minimum Volume
0.5 mL