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HelpOrder Code LABGOR, LD Lactate Dehydrogenase (LDH), Serum
Reporting Name
Lactate Dehydrogenase (LD), SUseful For
Investigation of a variety of diseases involving the heart, liver, muscle, kidney, lung, and blood
Monitoring changes in tumor burden after chemotherapy; lactate dehydrogenase elevations in patients with cancer are too erratic to be of use in the diagnosis of cancer
Testing Algorithm
For more information see Multiple Myeloma: Laboratory Screening
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumNecessary Information
Patient's age is required.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Ambient (preferred) | 7 days | |
| Frozen | 30 days | ||
| Refrigerated | 48 hours |
Special Instructions
Reference Values
1-30 days: 135-750 U/L
31 days-11 months: 180-435 U/L
1-3 years: 160-370 U/L
4-6 years: 145-345 U/L
7-9 years: 143-290 U/L
10-12 years: 120-293 U/L
13-15 years: 110-283 U/L
16-17 years: 105-233 U/L
≥18 years: 122-222 U/L
Day(s) Performed
Monday through Sunday
CPT Code Information
83615
Method Description
Lactate and nicotinamide adenine dinucleotide (NAD[+]), in the presence of lactate dehydrogenase (LD), are converted to pyruvate and NADH. The rate at which NADH is formed is determined by an increase in absorbance and is directly proportional to enzyme activity.(Package insert: LDH reagent. Roche Diagnostics; 08/2019)
Reject Due To
| Gross hemolysis | Reject |
Method Name
Photometric Rate Reaction