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HelpOrder Code LABOPITM Opiate Confirmation, Meconium
Additional Codes
| Mayo Test ID |
|---|
| OPATM |
Reporting Name
Opiate Confirmation, MUseful For
Detecting maternal prenatal opiate/opioid use up to 5 months before birth
Specimen Type
MeconiumOrdering Guidance
For chain-of-custody testing, order OPTMX / Opiate Confirmation, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Specimen Minimum Volume
0.3 g (approximately 1/4 teaspoon)
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Meconium | Frozen (preferred) | 28 days | |
| Refrigerated | 28 days | ||
| Ambient | 14 days |
Reject Due To
| Grossly bloody | Reject; Pink OK |
| Stool Diapers |
Reject |
Reference Values
Negative
Positives are reported with a quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) result.
Cutoff concentrations for LC-MS/MS testing:
Codeine: 20 ng/g
Hydrocodone: 20 ng/g
Hydromorphone: 20 ng/g
Morphine: 20 ng/g
Oxycodone: 20 ng/g
Oxymorphone: 20 ng/g
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Day(s) Performed
Monday through Sunday
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT Code Information
80361
80365
G0480 (if appropriate)
Method Description
Meconium is mixed with internal standard and extracted with methanol. The methanolic extract is further processed by solid phase extraction. The extract is analyzed by liquid chromatography tandem mass spectroscopy.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.