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Order Code LABROC Rubeola (Measles) Antibodies, IgG and IgM, Spinal Fluid

Additional Codes

Mayo Test Code: ROC

Reporting Name

Rubeola (Measles) Ab, IgG,IgM, CSF

Useful For

Diagnosing central nervous system rubeola (measles) virus infection and/or subacute sclerosing panencephalitis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

CSF


Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 0.25 mL


Specimen Minimum Volume

0.1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

IgG: <1:5

IgM: <1:10

Reference values apply to all ages.

Day(s) Performed

Monday through Friday

CPT Code Information

86765 x 2

Method Description

Cerebrospinal fluid (CSF) from a patient is reacted with the antigen substrate. Antibodies, if present, will bind to the antigen forming stable antigen-antibody complexes. If no antibodies are present, the complexes will not be formed and CSF components will be washed away. Fluorescein labeled antihuman IgG or IgM antibody is added to the reaction site which binds with the complexes formed. This results in a positive reaction of bright apple-green fluorescence when viewed with a properly equipped fluorescence microscope. If no complexes are formed, the fluorescein labeled antibody will be washed away, exhibiting a negative result.(Package insert: Measles Virus Antigen Substrate Slide. AESKU.BION, 9/2019)

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Method Name

Immunofluorescence Assay (IFA)

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.