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Order Code LABTHCM 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Meconium

Additional Codes

Mayo Test ID
THCM

Reporting Name

Carboxy-THC Confirmation, M

Useful For

Detecting in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth

Specimen Type

Meconium


Ordering Guidance


For chain-of-custody testing, order THCMX / 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen (preferred) 28 days
  Refrigerated  21 days
  Ambient  14 days

Reject Due To

Grossly bloody Reject; Pink OK
Stool
Diapers
Reject

Reference Values

Negative

Positives are reported with a quantitative liquid chromatography tandem mass spectrometry result.

Cutoff concentration: 5 ng/g

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Day(s) Performed

Monday through Sunday

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

CPT Code Information

80349

G0480 (if appropriate)

Method Description

Meconium is mixed with internal standard and extracted with methanol. The methanolic extract is further processed by solid phase extraction. The extract is analyzed by liquid chromatography tandem mass spectroscopy.(Unpublished Mayo method)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.