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Order Code LABUNHB Hemoglobin Stability, Blood

Reporting Name

Hb Stability, B

Useful For

Work-up of congenital hemolytic anemias

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole Blood EDTA


Specimen Required


Only orderable as part of a profile or as a reflex. For more information see:

-HAEV1 / Hemolytic Anemia Evaluation, Blood

-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

-REVE2 / Erythrocytosis Evaluation, Blood

-MEV1 / Methemoglobinemia Evaluation, Blood

 

Container/Tube: Lavender top (EDTA)

Specimen Volume: 4 mL


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated 7 days

Reference Values

Only orderable as part of a profile or as a reflex. For more information see:

-HAEV1 / Hemolytic Anemia Evaluation, Blood

-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

-REVE2 / Erythrocytosis Evaluation, Blood

-MEV1 / Methemoglobinemia Evaluation, Blood

 

Normal (reported as normal [stable] or abnormal [unstable])

CPT Code Information

83068

Method Description

Unstable hemoglobins precipitate in dilute solutions of isopropanol. Washed erythrocytes are hemolyzed and cleared by centrifugation. Isopropanol is added. The hemolysate is incubated at 37° C for 20 minutes and examined for turbidity. There is no turbidity with normal hemoglobins.(Schmidt RM: Laboratory diagnosis of hemoglobinopathies. In: Bick RL ed. Hematology Clinical and Laboratory Practice. Mosby-Year Book Inc; 1993:327-389; Greene DN, Vaughn CP, Crews BO, Agarwal AM. Advances in the detection of hemoglobinopathies. Clin Chim Acta. 2015;439:50-57)

Method Name

Only orderable as part of a profile or as a reflex. For more information see:

-HAEV1 / Hemolytic Anemia Evaluation, Blood

-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

-REVE2 / Erythrocytosis Evaluation, Blood

-MEV1 / Methemoglobinemia Evaluation, Blood

 

Isopropanol and Heat Stability

Reject Due To

Gross hemolysis Reject

Day(s) Performed

Monday through Friday