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HelpOrder Code LABUNHB Hemoglobin Stability, Blood
Reporting Name
Hb Stability, BUseful For
Work-up of congenital hemolytic anemias
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Whole Blood EDTASpecimen Required
Only orderable as part of a profile or as a reflex. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
-REVE2 / Erythrocytosis Evaluation, Blood
-MEV1 / Methemoglobinemia Evaluation, Blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 4 mL
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood EDTA | Refrigerated | 7 days |
Reference Values
Only orderable as part of a profile or as a reflex. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
-REVE2 / Erythrocytosis Evaluation, Blood
-MEV1 / Methemoglobinemia Evaluation, Blood
Normal (reported as normal [stable] or abnormal [unstable])
CPT Code Information
83068
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| UNHB | Hb Stability, B | 4639-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 9095 | Hb Stability, B | 4639-1 |
Method Description
Unstable hemoglobins precipitate in dilute solutions of isopropanol. Washed erythrocytes are hemolyzed and cleared by centrifugation. Isopropanol is added. The hemolysate is incubated at 37° C for 20 minutes and examined for turbidity. There is no turbidity with normal hemoglobins.(Schmidt RM: Laboratory diagnosis of hemoglobinopathies. In: Bick RL ed. Hematology Clinical and Laboratory Practice. Mosby-Year Book Inc; 1993:327-389; Greene DN, Vaughn CP, Crews BO, Agarwal AM. Advances in the detection of hemoglobinopathies. Clin Chim Acta. 2015;439:50-57)
Method Name
Only orderable as part of a profile or as a reflex. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
-REVE2 / Erythrocytosis Evaluation, Blood
-MEV1 / Methemoglobinemia Evaluation, Blood
Isopropanol and Heat Stability
Reject Due To
| Gross hemolysis | Reject |
Day(s) Performed
Monday through Friday