Sign in →

Order Code OLIGC Oligoclonal Banding, Spinal Fluid


Specimen Required


Only orderable as part of a profile. For more information, see:

-OLIG / Oligoclonal Banding, Serum and Spinal Fluid

-MSP3 / Multiple Sclerosis (MS) Profile, Serum and Spinal Fluid

 

Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 0.5 mL

Collection Instructions: Label specimen as spinal fluid.


Useful For

Diagnosis of multiple sclerosis; especially useful in patients with equivocal clinical presentation and radiological findings

Method Name

Only orderable as part of a profile. For more information, see:

-OLIG / Oligoclonal Banding, Serum and Spinal Fluid

-MSP3 / Multiple Sclerosis (MS) Profile, Serum and Spinal Fluid

 

Isoelectric Focusing (IEF) with IgG Immunoblot Detection

Reporting Name

CSF Bands

Specimen Type

CSF

Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Only orderable as part of a profile. For more information, see:

-OLIG / Oligoclonal Banding, Serum and Spinal Fluid

-MSP3 / Multiple Sclerosis (MS) Profile, Serum and Spinal Fluid

 

Cerebrospinal fluid Oligoclonal Bands Interpretation: <2 bands

Method Description

The oligoclonal band (OCB) assay requires paired cerebrospinal fluid (CSF) and serum samples. Unconcentrated CSF and diluted serum are electrophoresed by isoelectric focusing. The separated immunoglobulins (Ig) are visualized by an IgG immunoblot, and OCBs that are present in the CSF and not in the serum are reported. The assay uses reagents from Helena Laboratories.(Keir G, Luxton RW, Thompson EJ: Isoelectric focusing of cerebrospinal fluid immunoglobulins G: an annotated update. Ann Clin Biochem. 1990;27:436-443; Hortin GL: Amino Acids, Peptides, and Proteins. In: Burtis CA, Burns DE, Sawyer BG, eds. Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th ed. Elsevier; 2015:chap 18)

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83916