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HelpOrder Code OXYMS Oxymorphone and Metabolite, Serum
Ordering Guidance
This test should only be ordered by healthcare professionals to monitor patients who have been prescribed oxymorphone.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Monitoring therapeutic efficacy/compliance in serum specimens of patients who are prescribed oxymorphone
Detection and quantification of oxymorphone and noroxymorphone in serum
Special Instructions
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Oxymorphone and metabolite, SSpecimen Type
Serum RedSpecimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 24 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Therapeutic range/Metabolite information (as applicable)
Oxymorphone: 1.0-8.0 ng/mL
Noroxymorphone: Metabolite of oxymorphone
Cutoff concentrations:
Oxymorphone: 1.0 ng/mL
Noroxymorphone: 1.0 ng/mL
Method Description
The opiates are extracted from serum using a solvent to precipitate proteins. The supernatant is removed and analyzed by liquid chromatography tandem mass spectrometry.(Unpublished Mayo method)
Day(s) Performed
Tuesday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
G0480
80365 (if appropriate for select payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| OXYMS | Oxymorphone and metabolite, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623460 | Oxymorphone - Free | 46974-2 |
| 623461 | Noroxymorphone - Free | In Process |