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HelpOrder Code POSA Posaconazole, Serum
Reporting Name
Posaconazole, SUseful For
Monitoring posaconazole therapy
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Within 2 hours of collection, centrifuge, and aliquot serum into plastic vial.
Specimen Minimum Volume
0.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reference Values
>700 ng/mL (trough)
Day(s) Performed
Monday through Saturday
CPT Code Information
80187
Method Description
Posaconazole is extracted by mixing serum samples with acetonitrile to precipitate proteins. The supernatant is removed and analyzed by a liquid chromatography tandem mass spectrometry method.(Unpublished Mayo method)
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.