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HelpOrder Code SCERG Saccharomyces cerevisiae Antibody, IgG, Serum
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Measuring IgG anti-Saccharomyces cerevisiae antibodies as a part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations
This test is not useful for determining the extent of disease in patients with inflammatory bowel disease or determining the response to disease-specific therapy including surgical resection of diseased intestine
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Saccharomyces cerevisiae Ab, IgG, SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimen | Reject |
Reference Values
Negative: <20.0 RU/mL
Positive: ≥20.0 RU/mL
Reference values apply to all ages.
Method Description
Immunoglobulin G (IgG) anti-Saccharomyces cerevisiae antibodies (ASCA) are measured by commercial, microtiter enzyme immunoassay. This assay uses polystyrene microtiter plates coated with purified mannan from the cell wall of S cerevisiae to capture antibodies from patient sera and horseradish peroxidase-conjugated anti-IgG antibodies to detect IgG ASCA. Results of the test for IgG ASCA are reported in relative units per milliliter (RU/mL).(Package insert: Anti-Saccharomyces cerevisiae ELISA (IgG). EUROIMMUN Medizinische Labordiagnostika AG; 5/2011)
Day(s) Performed
Tuesday, Thursday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86671