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Order Code SFINC Cerebrospinal Fluid (CSF) IgG Index, Spinal Fluid


Specimen Required


Only orderable as part of a profile. For more information see SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.

 

Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 1 mL

Collection Instructions: Label specimen as spinal fluid.


Useful For

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions using cerebrospinal fluid specimens

Method Name

Only orderable as part of a profile. For more information see SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.

 

Nephelometry

Reporting Name

IgG Index, CSF

Specimen Type

CSF

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Only orderable as part of a profile. For more information see SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.

 

CSF index: 0.00-0.70

CSF IgG: 0.0-8.1 mg/dL

CSF albumin: 0.0-27.0 mg/dL

CSF IgG/albumin: 0.00-0.21

CSF IgG synthesis rate: 0-12 mg/24 hours

Method Description

Cerebrospinal fluid (CSF) and serum IgG and CSF albumin are determined by immunonephelometry. The CSF IgG index and synthesis rate are calculated and reported. Albumin in serum is determined by turbidimetry (bromocresol green method). The serum IgG and albumin, CSF IgG and albumin, and serum and CSF IgG/albumin ratios are reported.(Instruction manual: Siemens Nephelometer II Operations. Siemens, Inc; Version 2.4, 07/2019)

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82042

82784