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HelpOrder Code SMAT Smooth Muscle Antibody Titer, Serum
Specimen Required
Only orderable as part of a reflex. For more information see SMAS / Smooth Muscle Antibody Screen, Serum.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial
Useful For
Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes
Testing Algorithm
If the smooth muscle antibody (SMA) screen is equivocal or positive, then the SMA titer will be performed at an additional charge.
Method Name
Only orderable as part of a reflex. For more information see SMAS / Smooth Muscle Antibody Screen, Serum.
Indirect Immunofluorescence
Reporting Name
Smooth Muscle Ab Titer, SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-Treated | Reject |
Reference Values
Only orderable as part of a reflex. For more information see SMAS / Smooth Muscle Antibody Screen, Serum.
Negative
Reference values apply to all ages.
Method Description
Serial dilutions of the patient's serum are added to fresh tissue from mouse stomach/kidney and incubated; fluorescein-conjugated antiglobulin is then added. The slides are read with a fluorescence microscope.(Package insert: Kallestad Mouse Stomach/Kidney. Bio-Rad Laboratories, Inc; 06/2022)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86015
Day(s) Performed
Monday through Saturday