Order Code SP7CS Septin-7 Antibody, Cell-Binding Assay, Serum
Specimen Required
Only orderable as a reflex. For more information see:
-ENS2 / Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum
-MDS2 / Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum
-MAS1 / Myelopathy, Autoimmune/Paraneoplastic Evaluation, Serum
Useful For
Detecting septin-7 IgG by cell-binding assay using serum specimens
Testing Algorithm
If the indirect immunofluorescence (IFA) pattern suggests septin-7, then this test and septin-7 antibody IFA titer will be performed at an additional charge.
Method Name
Only orderable as a reflex. For more information see:
-ENS2 / Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum
-MDS2 / Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum
-MAS1 / Myelopathy, Autoimmune/Paraneoplastic Evaluation, Serum
Cell-Binding Assay (CBA)
Reporting Name
Septin-7 CBA, SSpecimen Type
SerumSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 28 days | |
Frozen | 28 days | ||
Ambient | 72 hours |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Reference Values
Only orderable as a reflex. For more information see:
-ENS2 / Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum
-MDS2 / Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum
-MAS1 / Myelopathy, Autoimmune/Paraneoplastic Evaluation, Serum
Negative
Method Description
Patient specimen is applied to a composite slide containing transfected and nontransfected HEK-293 cells. After incubation and washing, fluorescein-conjugated goat-antihuman IgG is applied to detect the presence of patient IgG binding.(Package insert: IIFT: Neurology Mosaics, Instructions for the indirect immunofluorescence test. EUROIMMUN; FA_112d-1_A_UK_C13, 02/2019)
Day(s) Performed
Monday through Sunday
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
86255