Order Code ZONI Zonisamide, Serum
Additional Codes
| Mayo Test ID | 
|---|
| ZONI | 
Reporting Name
Zonisamide, SUseful For
Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing
Assessing medication compliance
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST is not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | 
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | 
| Ambient | 28 days | |
| Frozen | 28 days | 
Reject Due To
| Gross hemolysis | OK | 
| Gross lipemia | OK | 
| Gross icterus | OK | 
Reference Values
10-40 mcg/mL
Performing Laboratory
 Mayo Clinic Laboratories in Rochester
Day(s) Performed
Monday through Saturday
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
CPT Code Information
80203
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value | 
|---|---|---|
| ZONI | Zonisamide, S | 29620-2 | 
| Result ID | Test Result Name | Result LOINC Value | 
|---|---|---|
| 83685 | Zonisamide, S | 29620-2 | 
Method Description
The serum sample is deproteinated with acetonitrile containing the deuterium labeled internal standard. The protein precipitate is centrifuged, and a portion of the supernatant is diluted with mobile phase for detection by tandem mass spectrometry.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Neurology Specialty Testing Client Test Request (T732)
-Therapeutics Test Request (T831)